Eupatorium perfoliatum
·
Asteraceae
·
North America

Boneset

Indian sage, Crosswort

Useful parts

Above-ground parts

Key actions

Immunostimulant, Antibacterial, Anti-inflammatory, Analgesic

Active compounds

Phenolics, Flavonoids, Terpenoids, Essential oils

This Site is for Educational Use Only: The information on this page is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. I am not a licensed medical professional. Always consult a qualified healthcare provider before using any medicinal plants, especially if you are pregnant, nursing, taking medications, or have a medical condition.

Possible Proposed Uses

  • Flu
  • Fever
  • Bronchitis
  • Common cold

Mechanism of Action

Research pending

Possible Side Effects

  • Nausea
  • Vomiting
  • Diarrhea

Possible Drug Interactions

  • Liver-metabolized medications
  • Avoid if allergic to Asteraceae

Abigail's notes

A little somethin' somethin' coming soon.

Personal notes, research rabbit holes, and why this plant earned a spot in the cabinet. Check back as the database grows.

Last updated on:
May 13, 2026

Deeper research options for you (because I would never ask you to just take my word for it)

Eupatorium perfoliatum L.: phytochemistry, traditional use and current applications

https://pubmed.ncbi.nlm.nih.gov/22004891/

Boneset

https://medicinalgardens.web.unc.edu/boneset/

Boneset

https://www.britannica.com/plant/boneset

Disclaimer: The content on this website is provided for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. No provider-patient relationship is created by use of this site. The author makes no representations regarding the accuracy or completeness of the information and assumes no liability for any adverse effects resulting from the use of plants or remedies described herein.

Know your sources.
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Check the source, not just the headline

Who wrote it? What are their credentials? Who published it and why? A wellness blog and a peer-reviewed journal are not the same thing, even when they say the same words. Always click through to the original source.

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Check the date

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Follow the money

Who funded the study? A supplement company funding research on their own supplement is a conflict of interest. It's not automaticly a disqualification, but worth noting. Look for the "funding" or "disclosures" section of any study you read.

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Understand study types

Not all research is equal. A randomized controlled trial carries more weight than a case study or an animal study. "A study found..." could mean ten people in a lab or a decade-long population study. The difference matters enormously.

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Cross-reference everything

If only one source is saying something, be skeptical. If ten independent sources across different institutions, different countries, different decades are saying the same thing, you're getting warmer. Consensus is earned, not declared. Studies should be peer reviewed.

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Use the NIH and examine.com

The National Institutes of Health database (PubMed) is free and searchable. Examine.com aggregates supplement research without selling anything. Both are significantly more reliable than any wellness influencer, including me.