A horizontal underground stem that stores nutrients and can produce new shoots. Not a root, though it looks like one.
Abbreviation for "species" (plural). Used when referring to multiple species within a genus, e.g., Ephedra spp.
A taxonomic rank grouping related genera. E.g., Lamiaceae (mint family) includes lavender, rosemary, and basil.
The geographic region where a plant naturally evolved and grows without human introduction.
The specific parts of a plant (root, leaf, flower, seed, bark) that contain the active compounds used medicinally. Different parts of the same plant can have very different effects.
A compound that evaporates easily at room temperature, often responsible for scent. Essential oils are composed primarily of volatile compounds.
a vital chemical compound that acts as a neurotransmitter, carrying signals from nerves to other cells, including muscle cells, nerve cells, and gland cells. It is crucial for bodily functions, including heart regulation, vasodilation, and glandular secretions.
Examples: released during muscle contraction, heart rate reduction, hieghtened focus, digestion
acts as a local modulator, accumulating during cell stress (e.g., lack of oxygen) or high metabolic activity to protect tissues. They act as sensors of cellular stress, regulating energy supply, and are major targets of stimulants like caffeine.
non-toxic plants, herbs, and mushrooms that help the body manage, resist, and adapt to physical, chemical, or mental stress. They work by balancing the body’s systems (homeostasis) and reducing stress-induced fatigue, acting as "stress response modifiers" that regulate hormone reactions.
Examples: Ashwagandha, Asian Ginseng, Rhodiola, Cordyseps
Alkaloids are a diverse group of naturally occurring organic compounds that contain at least one nitrogen atom, and possess basic ("alkali-like") properties. Mostly produced by plants, bacteria, fungi, and animals, they are cause strong physiological effects on humans and animals.
Examples: Morphine, Caffeine, Nicotine, Atropine
a substance that relieves pain and discomfort without causing a loss of consciousness. Commonly referred to a painkillers, they work by reducing inflammation or altering how the brain receives pain signals.
Examples: Tyleonl, Ibuprofen, Aspirin, Opioids
a medication whose primary, original indication is not pain control, but which has been found to provide pain relief (analgesia) in specific, often chronic or complex, painful conditions.
Examples: anticonvulsants, antidepressants, corticosteroids, local anesthetics
a group of antiparasitic drugs that expel or destroy parasitic worms and other internal parasites from the body. These drugs work by interrupting the parasite's metabolic processes (e.g., inhibiting glucose uptake) or by causing paralysis, which makes the parasite lose its grip on the host's tissues and become expelled.
Examples: Enverm, Stromectol, Biltricide
act as natural colorants and powerful antioxidants, providing health benefits such as reducing inflammation. They are responsible for the vibrant colors in blueberries, raspberries, black rice, red grapes, and purple cabbage.
Examples: Cyanidin (red cabbage), Malvidin (red wine/grapes), Delphinidin (blueberries)
a pharmacological agent used to prevent or treat seizures and convulsions by controlling abnormal electrical activity in the brain. They reduce the frequency and severity of seizures, or halt ongoing seizures.
prevent or relieve muscle spasms, particularly in the smooth muscles of internal organs like the stomach, intestines, bladder, and uterus. They work by relaxing smooth muscle tissues, often acting as calcium channel inhibitors or by blocking neural signals that cause contractions.
aka anti-anxiety agents, that reduce the symptoms of anxiety, including fear, dread, and physical tension. They work by slowing down central nervous system activity, helping to "loosen" anxiety's hold on a person.
Examples: Benzodiazepines, SSRIs, beta-blockers, barbituates
relaxes the muscle bands surrounding the airways (bronchi) in the lungs, causing them to widen and making it easier to breathe. They are usually administered via inhalers or nebulizers.
Examples: Albuterol, Ipratropium, Serevent, Spiriva
increases the efficiency and force of heart muscle contractions. . By improving cardiac output, these agents help the heart pump more blood with each beat, often making them useful in treating conditions like heart failure.
Examples: Digoxin, Dobutamine, Hawthorn, and other cardiac glycosides, phosphodiesterase, and sympathomimetics
involves the temporary narrowing of blood vessels in the brain, often causing severe "thunderclap" headaches and potentially leading to strokes or seizures. This can manifest as Reversible Vasoconstruction Syndrome (RCVS) and should be treated by a doctor.
increase the concentration and duration of action of acetylcholine at neuromuscular junctions and brain synapses, enhancing cholinergic signaling. Drugs that inhibit cholinesterase are primarily used to manage neurodegenerative diseases and neuromuscular conditions.
Examples: Aricept, Exelon, Razadyne
substances that mimic or enhance the action of the neurotransmitter acetylcholine, typically acting on the parasympathetic nervous system.
Examples: nicotine, bethanechol, pilocarpine
substances that slow brain activity, commonly used to treat anxiety, panic, and sleep disorders by inducing sedation and muscle relaxation. CNS stands for Central Nervous System.
Examples: xanax, valium, ambien, alcohol
substances that speed up brain activity, increasing alertness, energy, and focus. NS stands for Central Nervous System.
Examples: amphetamines, caffeine, nicotine, Vynase, Adderall
substances designed to improve mental faculties such as memory, focus, alertness, and executive function. While they may help mask boredom or fatigue, they often do not increase raw intelligence.
Examples: caffeine, Donepezil, Adderall, Aricept, Creatine, Lion's Mane mushroom
a specific situation (a symptom, condition, or drug interaction) where a treatment, medicine, or procedure should not be used because it may be harmful to the patient.
Examples: Acutane & pregnancy, Aspirin and children, MRI & metal, surgery during infection, etc.
a natural plant toxins that release hydrogen cyanide when broken down, acting as a defense mechanism against herbivores. When the plant tissue is damaged (e.g., chewing, crushing), enzymes break down the glycosides, releasing poisonous hydrogen cyanide.
Examples: linamarin found in cassave, amygdalin dound in stone fruit seeds
a substance that's mucilaginous (slimy, or oily) that forms a soothing, protective film over mucous membranes to relieve minor pain, inflammation, and irritation.
Examples: liquorice root, honey, and found in cough drops
help remove excess fluid from the body by increasing urine output, commonly treating high blood pressure, heart failure, and edema.
Examples: Hydrochlorothiazide, Furosemide, Spironolactone
a change in the way a drug acts in the body when taken with other substances, including other medications, food, beverages, or supplements, or when affected by an underlying medical condition. Can be drug to drug, drug to food/drink, or drug to condition.
concentrated, volatile hydrophobic liquids extracted from plants (flowers, leaves, roots, bark, seeds) that retain the natural smell, flavor, and compounds of the source. They are commonly used in aromatherapy, perfumes, cosmetics, and food flavorings, often produced via steam distillation or expression.
Examples: lavender, peppermint, tea tree, eucalyptus
plant-based pigments and antioxidants that provide significant health benefits, found commonly in berries, citrus fruits, dark chocolate, tea, and onions.
Examples: quercetin in apples, hersperidin in citrus, catechins in tea
specialized proteins in the brain that respond to gamma-aminobutyric acid (GABA), the primary neurotransmitter responsible for inhibiting, calming, or turning off nerve cell signals in the central nervous system (CNS). They reduce neuronal excitability, helping to regulate anxiety, sleep, and muscle tone
Examples: Barbiturates, Benzodiazepines, Alcohol, Ambien
the principal active compounds found naturally in the roots, stems, and leaves of the Panax (ginseng) plant family, including Asian, American, and notoginseng varieties. They are a class of steroid glycosides and triterpenoid saponins responsible for ginseng's well-known pharmacological effects. Their molecular structures allow them to affect multiple metabolic and cellular pathways, they exhibit a wide array of physiological effects.
substances that cause damage to the liver (hepatotoxicity).
Examples: Acetaminophen, antibiotics, NSAIDs, immunosuppressants
your body’s primary stress response system. HPA stands for Hypothalamic-Pituitary-Adrenal axis. It connects the brain to the adrenal glands and regulates immune functin, digestion, mood, and more.
a substance that boosts the body’s immune system, increasing its ability to fight infections, diseases, and cancer.
Examples: Lenalidomide, Mozobil, Imunovir, Promalidomide
psychoactive, lipophilic compounds found in the roots of the kava plant. ), which is native to the South Pacific islands. They are the active ingredients responsible for kava's, relaxing, sedative, and potential anxiety-reducing properties.
n enzyme that breaks down neurotransmitters like serotonin, dopamine, and norepinephrine. They work by stopping the breakdown of neurotransmitters, allowing them to remain in the brain longer, thus improving mood.
Examples: Phenelzine, Selegiline, Marplan, Parnate
blocks the reabsorption of neurotransmitters back into the presynaptic nerve cell. This process increases the availability of these neurotransmitters to stimulate post-synaptic receptors for a longer duration, which helps modulate mood, attention, and other functions.
Example: SSRISs (Prozac, Zoloft), SNRIs (Effexor), NDRIs (Wellbutrin)
an imbalance between free radicals and antioxidants in the body, leading to cell and tissue damage. This imbalance occurs when free radicals outnumber antioxidants, leading to damage in cells, proteins, and DNA.
Examples: premature aging, chronic inflammation, diabetes, cancer
the process where blood cells called platelets clump together to form a plug at the site of a damaged blood vessel, preventing excessive bleeding. This crucial step in hemostasis follows initial platelet adhesion and helps stop bleeding by creating a seal (like a scab).
an abnormal skin or body reaction to UV light or sunlight, resulting in rashes, intense sunburns, hives, or pain. Can be medeication or condition induced.
refers to chemical substances that act on the central nervous system to alter brain function. This results in temporary changes to perception, mood, consciousness, cognition, or behavior.
Examples: stimulats, depressants, hallucinogens, pschotherapeutics, cannabinoids
natural, plant-derived chemical compounds (glycosides) known for creating soap-like foam when mixed with water. They act as natural pest deterrents for plants. In human health, they may assist in lowering cholesterol and have potential anticancer properties, though they can also be toxic to some animals.
Examples: glycyrrhizin in licorice, soyasponins in soybeands, diosgenin in wild yam
a herbal preparation processed to guarantee a specific, consistent concentration of active compounds in every batch, usually expressed as a specific percentage.
Examples: turmeric (95% curcuminoids), milk thistle (80% silymarin), Ginkgo biloba (24% flavone glycosides)
a component of the autonomic nervous system that triggers the body’s "fight-or-flight" response, preparing it for stressful, dangerous, or physically demanding situations.
Examples: increased heart rate, alertness
a type of heart arrhythmia where the heart beats faster than normal.
Examples: a resting heart rate over 100 beats per minute (bpm)
astringent, polyphenolic compounds found in many plants, bark, wood, leaves, and fruit, known for creating a drying, bitter sensation in the mouth.
Examples: red wine, tea, dark chocolate, pomegranates, walnuts, pecans
a large, diverse class of naturally occurring organic chemicals. In plants, they are responsible for aromatic qualities (scent), pigmentation (color), and defense against herbivores and pathogens.
Examples: menthols, camphor, cannabinoids
a bitter, white alkaloid found primarily in cacao beans, tea, and cola nuts. It functins as a mild stimulant, vasodilator, and diuretic. It causes the bitter taste in dark chocolate.

Who wrote it? What are their credentials? Who published it and why? A wellness blog and a peer-reviewed journal are not the same thing, even when they say the same words. Always click through to the original source.

Science updates over time. A 2003 study on a supplement may have been contradicted twelve times since. Always look for the publication date and whether newer research exists. "Studies show" means nothing without a timestamp.

Who funded the study? A supplement company funding research on their own supplement is a conflict of interest. It's not automaticly a disqualification, but worth noting. Look for the "funding" or "disclosures" section of any study you read.

Not all research is equal. A randomized controlled trial carries more weight than a case study or an animal study. "A study found..." could mean ten people in a lab or a decade-long population study. The difference matters enormously.

If only one source is saying something, be skeptical. If ten independent sources across different institutions, different countries, different decades are saying the same thing, you're getting warmer. Consensus is earned, not declared. Studies should be peer reviewed.

The National Institutes of Health database (PubMed) is free and searchable. Examine.com aggregates supplement research without selling anything. Both are significantly more reliable than any wellness influencer, including me.